Key result
Anulom Vilom Pranayama reduces LF/HF ratio by ~1.43 and improves cognition in Parkinson's disease.
Why the study?
Patients with Parkinson's disease often experience cardiac autonomic dysfunction, cognitive impairment, and psychological disturbances, and limitations in current treatments warrant simple, cost-effective adjuvant therapies.
Does 12-week practice of Anulom Vilom Pranayama improve cardiac autonomic balance, cognition, psychological status, and quality of life in individuals with mild-to-moderate Parkinson's disease?
Population
86 individuals aged 35-70 years with mild-to-moderate Parkinson's disease
Comparison
Anulom Vilom Pranayama adjunctive to conventional treatment vs conventional treatment only
Design
Randomized controlled trial
Follow-up
12 weeks
Authors
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AVP offers a low-cost adjunct for autonomic dysfunction in PD; extends RCT evidence for pranayama in neurodegenerative disease.
RCT (n=86)
Open-label
Block randomization using computer-generated random numbers with varying blocks
No
Does 12-week practice of Anulom Vilom Pranayama improve cardiac autonomic balance, cognition, psychological status, and quality of life in individuals with mild-to-moderate Parkinson's disease?
Absolute Event Rate: 1.43% vs 0.19%
p-value: p=<0.05
A 12-week practice of Anulom Vilom Pranayama significantly improved cardiac sympathovagal balance, cognition, and quality of life in patients with mild-to-moderate Parkinson's disease.
Dhanaradja et al. (2025) conducted an RCT in Mild-to-moderate Parkinson's disease (n=86). Anulom Vilom Pranayama vs. Conventional treatment alone was evaluated on Change in LF/HF ratio from baseline to 12 weeks (p=<0.05). Twelve weeks of Anulom Vilom Pranayama significantly reduced the LF/HF ratio (mean reduction 1.43 vs 0.19) and improved cognition, psychological status, and quality of life in patients with mild-to-moderate Parkinson's disease.
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