Key result
Transcatheter aortic valve implantation was associated with a significantly lower incidence of postoperative delirium compared to surgical aortic valve replacement (44% vs 66%) in octogenarians.
Why the study?
Does transcatheter aortic valve implantation reduce postoperative delirium compared to surgical aortic valve replacement in octogenarians with severe aortic stenosis?
Population
143 consecutive octogenarian patients with severe aortic stenosis undergoing elective TAVI or SAVR. Mean age…
Comparison
Transcatheter aortic valve implantation (TAVI) vs Surgical aortic valve replacement (SAVR)
Design
Cohort
Follow-up
5 days postoperative
Authors
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Supports considering TAVI to reduce delirium risk in octogenarians; leaves open confirmation by randomized trials.
Cohort (n=143)
No
Does transcatheter aortic valve implantation reduce postoperative delirium compared to surgical aortic valve replacement in octogenarians with severe aortic stenosis?
Odds Ratio: 0.43 (95% CI 0.21–0.85)
Absolute Event Rate: 44% vs 66%
p-value: p=0.013
In octogenarians with severe aortic stenosis, TAVI is associated with a significantly lower risk and more predictable time course of postoperative delirium compared to SAVR.
Eide et al. (2015) conducted a cohort in Severe aortic stenosis (n=143). Transcatheter aortic valve implantation (TAVI) vs. Surgical aortic valve replacement (SAVR) was evaluated on Incidence of postoperative delirium within 5 days (OR 0.43, 95% CI 0.21-0.85, p=0.013). Transcatheter aortic valve implantation was associated with a significantly lower incidence of postoperative delirium compared to surgical aortic valve replacement (44% vs 66%) in octogenarians.
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