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June 20, 2026Radiology Case ReportsOpen Access

Hepatocellular carcinoma muscle and skin metastasis: A case-report

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Authors

MDMahyar DaskarehRAReihaneh Mortazavi ArdestaniAAAli Nosrati Andevari

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Overview

Case report reveals skin and musculoskeletal metastasis in hepatocellular carcinoma, suggesting new management considerations.

Key Points

  • This report highlights the unusual occurrence of muscle and skin metastases in a patient with hepatocellular carcinoma.
  • A 55-year-old patient with chronic hepatitis B and hepatocellular carcinoma underwent primary therapeutic resection.
  • Postoperative follow-up imaging revealed rising alpha-fetoprotein levels, leading to a contrast-enhanced MRI of the abdomen.
  • Imaging identified a suspicious abdominal wall lesion, requiring differential diagnosis of soft tissue lesions.
  • Imaging demonstrated a lesion in the abdominal wall post-surgery, indicating potential metastasis.
  • Musculoskeletal and cutaneous metastases from hepatocellular carcinoma were confirmed, despite being uncommon.
  • The findings call for thorough evaluations of skin and musculoskeletal regions in patients with hepatocellular carcinoma.

Cite This Study

Daskareh et al. (2026) studied this question.

synapsesocial.com/papers/6a362de1db0793dc1a535d59https://doi.org/10.1016/j.radcr.2026.05.067
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