What question did this study set out to answer?

This study aims to evaluate the incidence and impact of psychiatric disorders and cognitive changes in patients undergoing autologous hematopoietic stem cell transplantation.

June 20, 2026The Egyptian Journal of HaematologyOpen Access

The psychiatric illnesses in autologous hematopoietic stem cell transplantation patients: incidence, risk factors, and outcome

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Authors

DEDina G.E. ElsaiedTanta University MSMohamed A. SafaTanta University ARAhmed O.A.R. El RasoolTanta University

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Implication

Retrospective study assesses psychiatric and cognitive outcomes after autologous stem cell transplantation, suggesting the need for ongoing monitoring.

Key Points

This study aims to evaluate the incidence and impact of psychiatric disorders and cognitive changes in patients undergoing autologous hematopoietic stem cell transplantation.
Retrospective study involving 55 patients aged 18–65 years treated at Tanta University Bone Marrow Transplantation Unit.
Psychiatric and cognitive assessments were conducted at pre-conditioning, one day post-infusion, and three months post-transplant.
Standardized tools like SCID-I and Montreal Cognitive Assessment were used for evaluations.
Cognitive and psychiatric functions showed significant fluctuations during transplantation, especially during the neutropenic phase (P < 0.001).
Hodgkin lymphoma patients had poorer cognitive outcomes compared to multiple myeloma patients (P < 0.001).
Correlations were found between higher prior regimens, more CD34+ cell doses, delayed engraftment, and worse cognitive performance.

Cite This Study

Elsaied et al. (2026) studied this question.

synapsesocial.com/papers/6a362ebddb0793dc1a5366c9 https://doi.org/10.4103/ejh.ejh_143_25

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Implication

Retrospective study assesses psychiatric and cognitive outcomes after autologous stem cell transplantation, suggesting the need for ongoing monitoring.

The psychiatric illnesses in autologous hematopoietic stem cell transplantation patients: incidence, risk factors, and outcome

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Implication

Key Points

Cite This Study

The psychiatric illnesses in autologous hematopoietic stem cell transplantation patients: incidence, risk factors, and outcome

Discussion

Member takes

Implication

Key Points

Cite This Study

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