Transfersomes-based nanocarriers for anticancer drug delivery: a promising approach

Chemotherapy is typically used to treat cancer, but it can have a number of negative side effects. Nanocarrier-based drug delivery systems have gained much interest cancer treatment in recent years due to their advantages compared to conventional delivery systems. Recently, transfersomes (TFs) have been known to be the most outstanding innovative drug delivery systems that make them an attractive carriers for drug administration and cancer therapy. TFs have a bilayered structure that facilitates the encapsulation of lipophilic and hydrophilic drugs/agents with higher permeation efficiencies, offering a promising alternative to conventional liposomes as an anti-cancer drug delivery method. They are highly interesting for applications that involve controlled release. TFs are being explored as a complex system for drug delivery, with a focus on enhancing local drug penetration. This paper overview the current advancements in transfersomes-encapsulated with anti-cancer drugs for intelligent medication delivery to various cancers. In conclusion, this paper briefly discusses the prospects and problems of transfersomes-based anti-cancer drug delivery.