Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
June 20, 2026CancersOpen Access

Transarterial Chemoembolization Versus Transarterial Radioembolization in Hepatocellular Carcinoma: A Systematic Review and Meta-Analysis of Real-World and Clinical Trial Evidence

View Full Paper
Ask AI
Bookmark
Share

Authors

PGPriyanka GognaCWCindy WangDUDex Underwood

Discussion

Loading...

Member takes

Overview

Systematic review evaluates TARE versus TACE for overall survival and safety in HCC, suggesting similarity in outcomes.

Key Points

  • This meta-analysis aims to compare the effectiveness and safety of TARE versus TACE in treating hepatocellular carcinoma.
  • Conducted a systematic literature review and meta-analysis per PRISMA guidelines.
  • Searched PubMed and Embase for studies from 2015 to 2025, identifying RCTs and observational studies on TARE and TACE.
  • Analyzed outcomes including overall survival, objective response rate, progression-free survival, and adverse events.
  • No significant difference in overall survival between TARE and TACE (HR: 0.99; 95% CI 0.70–1.39).
  • Objective response rate was comparable (RR: 0.94; 95% CI 0.84–1.05).
  • Progression-free survival favored TARE, but not statistically significant (HR: 0.54; 95% CI 0.29–1.01).

Cite This Study

Gogna et al. (2026) studied this question.

synapsesocial.com/papers/6a3630f5db0793dc1a53802chttps://doi.org/10.3390/cancers18121985
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Radioembolization versus chemoembolization for unresectable hepatocellular carcinoma: a meta-analysis of randomized trials2018 · 74 citations
  2. 2Radiation Segmentectomy for the Treatment of Hepatocellular Carcinoma: A Practical Review of Evidence2024 · 8 citations
  3. 3Y90 Radioembolization Significantly Prolongs Time to Progression Compared With Chemoembolization in Patients With Hepatocellular Carcinoma2016 · 693 citations
  4. 4Treatment for Hepatocellular Carcinoma with Portal Vein Tumor Thrombosis: The Emerging Role for Radioembolization Using Yttrium-902013 · 152 citations
  5. 5Transarterial Y90 radioembolization versus chemoembolization for patients with hepatocellular carcinoma: A meta-analysis2015 · 69 citations