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June 20, 2026Acta chimica slovenicaOpen Access

Synthesis, crystal structures and urease inhibition of isostructural tetranuclear nickel(II)-zinc(II) complexes derived from 2-(((2-hydroxyphenyl)imino) methyl)-6-methoxyphenol

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Authors

PLPeng LiangHNHai-Bo Niu

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Overview

Randomized trial investigates urease inhibition in nickel-zinc complexes, suggesting potential applications.

Key Points

  • To synthesize and characterize tetranuclear nickel(II)-zinc(II) complexes and evaluate their urease inhibitory activity.
  • Prepared three isostructural complexes with elemental analysis, IR, and UV-Vis spectroscopy.
  • Confirmed molecular structures using single crystal X-ray diffraction.
  • Measured urease inhibitory activity with IC50 values reported.
  • The synthesized complexes showed IC50 values for urease inhibition between 3.2 and 3.6 μmol L–1.
  • Structurally characterized complexes display octahedral coordination for Ni and square pyramidal coordination for Zn.
  • Isostructural complexes were confirmed through detailed spectroscopic methods.

Cite This Study

Liang et al. (2026) studied this question.

synapsesocial.com/papers/6a3631a1db0793dc1a538762https://doi.org/10.17344/acsi.2026.9781
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