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June 20, 2026International Journal of Research in Pharmaceutical SciencesOpen Access

Phytochemical Profiling, Characterisation, and Antibacterial Potential of Syzygium aromaticum (Clove) Extracts Against Multidrug-Resistant Bacterial Strains

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Authors

DKDr. Amit KumarJSJasveer SinghSDShiv Dutt

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Overview

Randomized trial evaluates antibacterial effects of clove extracts in multidrug-resistant bacteria, indicating a natural source for antimicrobial agents.

Key Points

  • The study aims to evaluate the antibacterial activity of Syzygium aromaticum (clove) extracts against multidrug-resistant bacterial strains.
  • Clove bud extracts were prepared using n-hexane, acetone, and ethanol solvents.
  • Antibacterial activity was tested using agar well diffusion against Staphylococcus aureus, Bacillus subtilis, Escherichia coli, and Pseudomonas aeruginosa.
  • Qualitative phytochemical screening confirmed the presence of alkaloids, flavonoids, tannins, phenolic compounds, and terpenoids.
  • The n-hexane extract showed the highest zone of inhibition (up to 18 mm against S. aureus).
  • GC-MS analysis identified five major terpenoid constituents contributing to antibacterial activity.
  • The study indicates that lipophilic extracts, especially n-hexane, possess significant antibacterial potential against MDR organisms.

Cite This Study

Kumar et al. (2026) studied this question.

synapsesocial.com/papers/6a3632a0db0793dc1a539222https://doi.org/10.26452/ijrps.v17i2.4417
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