What question did this study set out to answer?

To assess the relationship between successful recanalization of cerebral arteries and functional outcomes in minor ischemic stroke patients.

June 20, 2026Stroke

Association of Successful Recanalization and Functional Outcomes in Minor Ischemic Stroke With Proven Occlusion: A Secondary Analysis of TEMPO-2 Trial

View Full Paper

Ask AI

Bookmark

Authors

NSNishita SinghUniversity of Manitoba DSDaniel StrbianBoston University SVShabnam VatanpourUniversity of Calgary

Discussion

Member takes

Implication

Randomized trial finds better functional recovery associated with successful recanalization in minor ischemic stroke patients, suggesting treatment impacts outcomes.

Key Points

To assess the relationship between successful recanalization of cerebral arteries and functional outcomes in minor ischemic stroke patients.
Secondary analysis of TEMPO-2 trial, a randomized controlled trial comparing tenecteplase with standard care.
Follow-up computed tomography angiography conducted 4-8 hours post-randomization for evaluation of successful recanalization.
Functional outcomes measured using modified Rankin Scale at 90 days.
Successful recanalization was associated with a primary outcome adjusted risk ratio of 1.21 (95% CI, 1.07–1.34).
Stroke progression rates were significantly lower in patients with successful recanalization (2.8%) compared to those without (13.1%), adjusted risk ratio 0.21 (95% CI, 0.08–0.52).
Tenecteplase was the strongest predictor of successful recanalization, with an odds ratio of 3.48 (95% CI, 2.33–5.18).

Cite This Study

Singh et al. (2026) studied this question.

synapsesocial.com/papers/6a3632fcdb0793dc1a5396f5 https://doi.org/10.1161/strokeaha.125.052872

View Full Paper

Ask AI

Bookmark

Implication

Randomized trial finds better functional recovery associated with successful recanalization in minor ischemic stroke patients, suggesting treatment impacts outcomes.

Association of Successful Recanalization and Functional Outcomes in Minor Ischemic Stroke With Proven Occlusion: A Secondary Analysis of TEMPO-2 Trial

Discussion

Member takes

Implication

Key Points

Cite This Study

Association of Successful Recanalization and Functional Outcomes in Minor Ischemic Stroke With Proven Occlusion: A Secondary Analysis of TEMPO-2 Trial

Discussion

Member takes

Implication

Key Points

Cite This Study

Also Consider

Also Consider