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June 21, 2026CureusOpen Access

Salmonella Typhi Osteomyelitis of the Ulnar Diaphysis in an Immunocompetent Adult: A Case Report

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Authors

SSSakshi SinghRMR. Maheshwari

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Overview

Case report reveals chronic osteomyelitis caused by Salmonella Typhi in an immunocompetent adult, emphasizing diagnostic challenges and treatment options.

Key Points

  • To report a rare case of chronic osteomyelitis caused by Salmonella Typhi in an immunocompetent adult.
  • Clinical examination revealed progressive pain and swelling in the left forearm over four months.
  • Laboratory tests showed normal inflammatory markers and imaging indicated chronic intramedullary osteomyelitis.
  • Treatment involved surgical sequestrectomy, antimicrobial therapy with ceftriaxone and cotrimoxazole, and obtaining tissue cultures.
  • Intraoperative cultures identified S. Typhi resistant to ciprofloxacin and levofloxacin but sensitive to ceftriaxone.
  • The patient achieved complete clinical and radiological recovery post treatment without recurrence.
  • Histopathological assessment confirmed the presence of chronic osteomyelitis.

Cite This Study

Singh et al. (2026) studied this question.

synapsesocial.com/papers/6a377edf24f042ddf4c59cf0https://doi.org/10.7759/cureus.111132
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Antimicrobial resistance in typhoidal and nontyphoidal salmonellae2008 · 292 citations
  2. 2Chronic Salmonella Osteomyelitis in a Healthy, Immunocompetent Man2021 · 2 citations
  3. 3Salmonella Osteomyelitis in Adults: A Systematic Review2021 · 33 citations
  4. 4Extra-Intestinal Manifestations of Salmonella Infections1987 · 652 citations