Reveals how RNA modifications regulate gene expression in bone metabolism, suggesting significant implications for metabolic diseases.
RNA undergoes various chemical modifications after transcription.These RNA modifications are found not only in mRNA but also in rRNA and tRNA, and function as posttranscriptional regulatory mechanisms that control RNA stability, decay, localization, translational efficiency, ribosome function, and translational fidelity.In recent years, RNA modification-mediated gene regulation has attracted increasing attention as a mechanism involved in development, differentiation, metabolism, and disease.Its importance is also
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Shoichiro Kokabu (2026) studied this question.
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