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June 21, 2026Revista Sangre (ENG)Open Access

Myeloproliferative neoplasms: recommendations for next-generation sequencing

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Authors

MGM.ª Teresa Gómez-CasaresBBBeatriz Bellosillo-ParicioABAdoración Blanco

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Overview

Consensus-based recommendations standardize next-generation sequencing in the molecular diagnosis of myeloproliferative neoplasms, suggesting implications for patient management.

Key Points

  • The aim is to establish recommendations for the standardized use of NGS in diagnosing myeloproliferative neoplasms.
  • Consensus recommendations were developed by the Molecular Biology in Hematology Group (GBMH) and a multidisciplinary expert panel.
  • Recent literature and international classifications (WHO, ICC, ELN) were reviewed to guide the recommendations.
  • Discussions conducted among experts facilitated the structured consensus development.
  • Guidelines were established for the application of targeted NGS panels to analyze multiple genetic alterations.
  • Genetic data were deemed critical for accurate diagnosis and risk stratification in hematologic neoplasms.
  • Recommendations highlighted specific genes and alterations based on available scientific evidence.

Cite This Study

Gómez-Casares et al. (2026) studied this question.

synapsesocial.com/papers/6a377fb224f042ddf4c5a094https://doi.org/10.24875/sangree.m26000054
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Acute myeloid leukemia: recommendations for next-generation sequencing2026
  2. 2Chronic lymphocytic leukemia: recommendations for next-generation sequencing2026
  3. 3Mantle cell lymphoma: recommendations for next-generation sequencing2026
  4. 4Large B-cell lymphoma: recommendations for next-generation sequencing2026
  5. 5The role of next-generation sequencing in hematologic malignancies2024 · 22 citations