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June 22, 2026BMC NephrologyOpen Access

Sexual dysfunction and effect on quality of life in chronic kidney disease: a systematic review and meta-analysis

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Authors

IEImuetinyan Rashida EdekiOAOluseyi Ademola AdejumoDODapo Sunday Oyedepo

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Overview

Systematic review estimates sexual dysfunction prevalence in chronic kidney disease, linking it to quality of life issues.

Key Points

  • This study aimed to estimate the prevalence of sexual dysfunction in chronic kidney disease and its association with quality of life.
  • Systematic review and meta-analysis of 44 studies
  • Included 10,672 participants from 18 countries
  • Used random-effects model and Fisher's Z transformation for analysis
  • Pooled prevalence of sexual dysfunction was 71.2% (95% CI: 65.9-76.3%)
  • Prevalence was highest in hemodialysis patients (77.6%) and lowest in post-kidney transplant recipients (56.9%)
  • Significant correlation found between sexual dysfunction and poorer mental (r ≈ 0.36, p < 0.001) and physical (r ≈ 0.39, p < 0.001) quality of life.

Cite This Study

Edeki et al. (2026) studied this question.

synapsesocial.com/papers/6a38d0a8da1bad9caca309cdhttps://doi.org/10.1186/s12882-026-05142-2
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Evaluation of relationship between sexual functions, depression and quality of life in patients with chronic kidney disease at predialysis stage2014 · 49 citations
  2. 2Erectile dysfunction and reproductive disorders in patients with chronic kidney disease2025
  3. 3Male sexual dysfunction in patients with chronic kidney disease: a cross-sectional study2024 · 12 citations
  4. 4(822) Sexual Dysfunction Among Men with Chronic Kidney Disease, an Enigma in a Low – Middle-Income Country2026
  5. 5Global prevalence of depression in chronic kidney disease: a systematic review and meta-analysis2024 · 63 citations