Key result
Colchicine and NSAIDs promptly improve Toxoplasma gondii myopericarditis symptoms in an immunocompetent young male.
Case Report (n=1)
Toxoplasma gondii is a rare but possible infectious cause of myopericarditis in immunocompetent individuals, which can be effectively evaluated with cardiac MRI.
May prompt Toxoplasma testing in myopericarditis beyond immunocompromised hosts; extends etiology spectrum but leaves management questions open.
Background and Clinical Significance: Inflammatory myopericardial syndrome is an umbrella term recently introduced by the European Society of Cardiology, which encapsulates the overlap that exists in clinical practice between myocardial and pericardial disease. It has a heterogeneous aetiology and a broad spectrum of severity in terms of its clinical features. Toxoplasma gondii is a rare but recognised infectious cause of myopericarditis and is typically seen in immunocompromised individuals. Case Presentation: We present the case of a young, immunocompetent male, presenting with pleuritic chest pain following a recent flu-like illness. Investigations revealed an acute myocardial injury based on elevated troponin T levels, in the absence of ventricular dysfunction. Toxoplasma immunoserology was consistent with primary toxoplasma infection. The remainder of his viral panel was negative. There was prompt symptom improvement following commencement of treatment with colchicine and a non-steroidal anti-inflammatory agent. Cardiac magnetic resonance imaging post-discharge revealed findings consistent with prior myocarditis. Conclusions: This case is an example of the rare occurrence of toxoplasma myopericarditis in an immunocompetent individual. Cardiac MRI is an invaluable imaging modality used to evaluate myocardial function and tissue characteristics in patients presenting with inflammatory myopericardial syndrome.
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Leahy et al. (2026) conducted a case report in Myopericarditis secondary to Toxoplasma gondii infection (n=1). Colchicine and a non-steroidal anti-inflammatory agent was evaluated on Symptom improvement and cardiac MRI findings. Toxoplasma gondii infection caused myopericarditis in an immunocompetent young male, with prompt symptom improvement following treatment with colchicine and a non-steroidal anti-inflammatory agent.
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