Key result
ABI <0.9 is linked to ~104% higher cardiovascular mortality in the asymptomatic general population.
Meta-Analysis (n=181,598)
Effect estimate: HR 2.04 (95% CI 1.70-2.44)
p-value: p=<.001
May support ABI-based risk stratification in asymptomatic adults; confirms prognostic value but leaves open whether screening improves outcomes.
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Messeder et al. (2026) conducted a meta-analysis in Asymptomatic general population (n=181,598). Ankle Brachial Pressure Index (ABPI) <0.9 vs. Normal ABPI was evaluated on Cardiovascular mortality (HR 2.04, 95% CI 1.70-2.44, p=<.001). An ankle brachial pressure index <0.9 was significantly associated with higher cardiovascular mortality (HR 2.04) compared with a normal index in the asymptomatic general population.
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