The authors advocate for a shift from strictly minimally invasive ECCO2R approaches toward a mid-flow strategy using peristaltic pumps to maximize clinical efficacy while mitigating shear stress.
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Gasca-Aldama et al. (2026) conducted a letter in Mild-to-moderate ARDS (n=78). Minimally invasive extracorporeal CO₂ removal (miECCO₂R) via peristaltic pumps was evaluated on Incidence of clinically significant hemolysis, major hemorrhages, or intracranial bleeding.
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