Key result
P-duration and PTFV1 correlate with LAVi and LV diastolic dysfunction, indicating left atrial overload.
Why the study?
Do electrocardiographic parameters correlate with echocardiographic markers of left atrial overload and diastolic dysfunction in patients with cardiac symptoms?
Cross-Sectional (n=200)
Yes
Do electrocardiographic parameters correlate with echocardiographic markers of left atrial overload and diastolic dysfunction in patients with cardiac symptoms?
Simple electrocardiographic parameters like P-duration and P terminal force in V1 can serve as reliable indicators of left atrial overload and correlate well with echocardiographic grades of diastolic dysfunction.
ECG P-wave indices may flag left atrial overload in symptomatic patients; leaves open their diagnostic utility pending prospective validation.
Background and objectives: Left atrial overload parameters in the electrocardiogram could suggest rising left atrial pressure that leads to heart disease. An increase in the Left atrial area and pressure are signs of left ventricle diastolic dysfunction. Therefore, we aimed to find the relationship between electrocardiogram and left ventricle diastolic function by echocardiography to assess left atrial overload. Methods: This observational, cross-sectional study enrolled 200 patients with cardiac symptom(s) from April 2024 to April 2025 at Sulaimani Cardiac Hospital and Faruk Medical City, using a convenient sampling method. The patients underwent electrocardiography and echocardiography. Later, the correlations between both techniques were determined in relation to left atrium overload in diastolic dysfunction. Results: Among studied patients, 51.5% had hypertension, 32.5% had diabetes, 19% had ischemic heart disease, 57.5% presented with shortness of breath, 38% with chest pain, 25.5%, with palpitation, 1.5% had aortic stenosis, 2.0% had aortic regurgitation, and 41% had diastolic dysfunction. Echocardiography showed that tricuspid regurgitation velocity and heart rate did not differ among the grades of diastolic dysfunction. P-duration exhibited a decent correlation with left atrial volume index (p<0.001), while P terminal force in V1 showed rational correlations with left atrial volume index and E/é (p<0.001). P-duration and P terminal force in V1 significantly correlated among left ventricle diastolic function grades (p<0.001). Conclusions: P-duration and P terminal force in V1 could indicate left atrial overload if electrocardiography and echocardiography are used to correlate grades of diastolic dysfunction.
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Muhammad et al. (2026) conducted a cross-sectional in Left ventricular diastolic dysfunction and left atrial overload (n=200). Electrocardiography (P-duration and PTFV1) vs. Echocardiography was evaluated on Correlation of P-duration with left atrial volume index (LAVi) (r=0.365, p=<0.001). P-duration and P terminal force in V1 significantly correlated with left atrial volume index and left ventricle diastolic dysfunction grades (p<0.001), indicating left atrial overload.
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