Key result
Left atrial enlargement correlates with lower RV function in patients with LVDD.
Why the study?
Few reports exist on the relationship between left ventricular diastolic dysfunction and its key features, such as left atrial enlargement and left ventricular hypertrophy, with right ventricular function.
Comparison
Patients with LVDD vs controls without LVDD
Authors
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LA enlargement may flag RV dysfunction in LVDD; hypothesis-generating, needs prospective validation before practice change.
Cross-Sectional (n=50)
Effect estimate: Pearson's r -0.4 and -0.38
p-value: p=≤ 0.001
Left atrial enlargement correlates with progressive right ventricular dysfunction in patients with left ventricular diastolic dysfunction.
Baroncini et al. (2019) conducted a cross-sectional in Left ventricular diastolic dysfunction (LVDD) (n=50). Left ventricular diastolic dysfunction (LVDD) vs. Patients without LVDD was evaluated on Correlation between left atrial size/volume and right ventricular function (TAPSE and RV lateral S') (Pearson's r -0.4 and -0.38, p=≤ 0.001). Left atrial enlargement was significantly correlated with lower right ventricular function (TAPSE and RV lateral S') in patients with left ventricular diastolic dysfunction (p ≤ 0.001).
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