The Prevalence of Left Ventricular Hypertrophy and Altered Geometry in Patients with Right Ventricular Diastolic Dysfunction

Background: Left ventricular diastolic dysfunction (LVDD) associated with left ventricular hypertrophy (LVH) been reported to play a major role in cardiovascular heart failure. Although, right ventricular diastolic dysfunction (RVDD) in patients with LVH was known to be clinically relevant, no systematic study had been performed regarding relationship between left ventricular (LV) geometry associated with LVH and RVDD. The goal of this study was evaluate an association between RVDD; LVDD, LVH and LV altered geometry for early diagnosis of heart failure. and Results: Out of 426 patients, 396 patients (93%) were found to have both RVDD and LVDD. In this , LV concentric geometry (LVCG) was identified in 138 patients (32.3%). RVDD and LVDD were diagnosed by of E/A and tissue doppler imaging (E’/A’) for mitral and tricuspid valves. The mean value of mitral E/A in LVCG group was lower than that of controls; 0.63±0.03 vs. 1.44±0.03, p<0.02. Mitral E’/A’ was also lower in LVCG that of controls; 0.60±0.02 vs. 1.36±0.03, p<0.01. Similarly, E/A of Tricuspid valve in patients with LVCG was found be lower than E/A of Tricuspid valve of controls; 0.52±0.07 vs. 0.69±0.02, p<0.001 and E’/A’ of tricuspid valve was than that of controls; 0.44±0.02 vs. 0.63±0.06, p<0.05. : This study demonstrated that simple doppler trans-valvular inflow parameters and tissue doppler may identify patients with biventricular diastolic dysfunction. This finding was more often observed in patients LV concentric geometry, a pattern associated with an increased risk of cardiovascular events.