Key result
Diabetes is linked to ~15% higher early mortality and stroke risk after AVR.
Why the study?
Diabetes mellitus is implicated in aortic valve stenosis development and adverse outcomes after aortic valve replacement, warranting a comprehensive review.
Does diabetes mellitus worsen treatment outcomes (mortality and stroke) after aortic valve replacement in patients with aortic valve stenosis?
Population
760,287 patients with AVS across 22 studies
Comparison
DM patients vs non-DM patients
Design
Meta-analysis
Authors
Loading...
DM prevalence near 31% signals major comorbidity burden; supports heightened mortality vigilance while extending pooled observational data.
Meta-Analysis (n=760,287)
Does diabetes mellitus worsen treatment outcomes (mortality and stroke) after aortic valve replacement in patients with aortic valve stenosis?
Odds Ratio: 1.15 (95% CI 1.03–1.28)
p-value: p=0.009
Diabetes mellitus is associated with a significantly higher risk of early mortality and stroke following aortic valve replacement in patients with aortic valve stenosis.
Hosseini et al. (2026) conducted a meta-analysis in Aortic valve stenosis (n=760,287). Diabetes mellitus vs. Non-diabetes mellitus was evaluated on Stroke (OR 1.15, 95% CI 1.03-1.28, p=0.009). Diabetes mellitus in patients with aortic valve stenosis was associated with significantly higher risks of early mortality and stroke (OR 1.15; 95% CI 1.03-1.28; P=0.009) after aortic valve replacement.