Key result
Surgical mitral valve repair with en bloc MitraClip excision eliminates recurrent severe MR.
Case Report (n=1)
En bloc resection of the MitraClip and involved leaflet tissue is a viable surgical strategy for treating recurrent severe mitral regurgitation due to late-phase single leaflet device attachment.
Late SLDA after TEER may cause recurrent MR; this case leaves open durability and surveillance needs.
An 87-year-old man underwent transcatheter edge-to-edge repair (TEER), one MitraClip NT︎ from anterior commissure (AC), 8 months prior for severe mitral regurgitation (MR) due to functional etiology and A1 chordal rupture, complicated by heart failure. Following improvement in heart failure, he was discharged home independently 2 weeks postprocedure. However, 4 months ago, he experienced worsening heart failure, and echocardiography revealed recurrent severe MR due to single leaflet device attachment (SLDA) at P1, prompting a surgical intervention. Intraoperatively, after establishing cardiopulmonary bypass and inducing cardiac arrest, transseptal access revealed the MitraClip NT︎ firmly adhered to the P1 leaflet and extensive rupture of the A1 chordae. The MitraClip NT︎ and involved leaflet tissue were excised en bloc, the defect was repaired, artificial chordae were implanted, edge-to-edge repair of the AC region was performed, and a prosthetic annuloplasty ring was sutured in place, successfully eliminating regurgitation. Since MitraClip NT︎ becomes encapsulated by fibrous tissue within 2-3 months postimplantation, isolated removal becomes technically difficult in the late phase. Therefore, en bloc resection with the leaflet is necessary in cases of SLDA-related recurrent MR. SLDA involving the posterior mitral leaflet is considered more amenable to mitral valve repair than that involving the anterior mitral leaflet. Patients selected for TEER generally have limited surgical tolerance; thus, minimizing operative and cardiopulmonary bypass times is essential. Surgical approach should be tailored based on leaflet morphology and clip location.
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Makiura et al. (2026) conducted a case report in Recurrent severe mitral regurgitation due to single leaflet device attachment following TEER (n=1). Surgical mitral valve repair (en bloc resection, artificial chordae, annuloplasty) was evaluated on Elimination of regurgitation. Surgical mitral valve repair with en bloc resection of the MitraClip and involved leaflet tissue successfully eliminated recurrent severe mitral regurgitation.
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