Key result
Bailout clipping using a larger XTW clip successfully managed a leaflet perforation during mitral transcatheter edge-to-edge repair, reducing mitral regurgitation to mild.
Why the study?
Leaflet tear and perforation are serious complications of TEER using the MitraClip system for severe MR, but no optimal bailout strategy has been established.
Case Report (n=1)
Bailout clipping using a longer clip arm (XTW) is a feasible strategy to manage leaflet perforation during transcatheter edge-to-edge repair.
May inform bailout for MitraClip leaflet perforation in unstable patients; leaves open optimal strategy.
Background: Leaflet tear and perforation are serious complications of transcatheter edge-to-edge repair (TEER) using the MitraClip system for severe mitral regurgitation (MR). However, no optimal bailout strategy has been established. Case summary: An 80-year-old woman developed heart failure due to acute ischaemic severe MR after primary percutaneous coronary intervention. Given the requirement for inotropic drugs and an intra-aortic balloon pump to stabilize her heart failure, we decided to perform TEER using the MitraClip G4 system. The NTW clip was selected considering the limited posterior leaflet, wide central MR, and delivery to the central A2/P2. The leaflet was successfully grasped, and the MR jet dramatically decreased while the clip was closed. However, the MR jet suddenly appeared after completely closing the clip arm. A new eccentric jet was detected coming from the mid-portion of the posterior leaflet, indicating leaflet perforation. We decided to manage the leaflet perforation by covering the perforated portion with a longer type of clip. An XTW clip was then carefully delivered to the previously grasped portion, after which we confirmed that the tip of the clip arm was positioned more posteriorly to the leaflet perforation. After slowly closing the clip, MR decreased to mild, with transoesophageal echocardiography showing no eccentric MR. After her haemodynamics stabilized, she was discharged 28 days after the procedure. Discussion: This case details a successful bailout clipping of a leaflet perforation using an XTW clip. Leaflet anatomy evaluation is important to ensure that the injured portion is covered by the longer clip arm.
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Nishiura et al. (2023) conducted a case report in Acute ischaemic severe mitral regurgitation and leaflet perforation (n=1). Bailout clipping using a larger clip size (XTW clip) was evaluated on Reduction of mitral regurgitation and hemodynamic stabilization. Bailout clipping using a larger XTW clip successfully managed a leaflet perforation during mitral transcatheter edge-to-edge repair, reducing mitral regurgitation to mild.
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