Surgical left atrial appendage occlusion during cardiac surgery was associated with more frequent prolonged inotropic support (40.8% vs. 34.7%; OR 1.29, 95% CI 1.13-1.47) compared to no S-LAAO.
Cohort (n=25,059)
Yes
Does the addition of surgical left atrial appendage occlusion (S-LAAO) worsen perioperative outcomes in adults undergoing valve or coronary bypass surgery?
The addition of surgical LAAO during valve or CABG surgery does not increase short-term mortality but is associated with a higher need for prolonged inotropic support.
Odds Ratio: 1.29 (95% CI 1.13–1.47)
Absolute Event Rate: 40.8% vs 34.7%
Surgical left atrial appendage occlusion (S-LAAO) is increasingly performed during cardiac surgery, but perioperative outcomes remain uncertain. Using a nationwide Japanese inpatient database, we analyzed 25,059 adults undergoing valve or coronary bypass surgery (2020 - 2022). After propensity score matching (n = 2,543 each), addition of S-LAAO was not associated with differences in in-hospital mortality, transfusion, reoperation, or 30-day readmission compared to non-S-LAAO group. However, prolonged inotropic support (≥ 2 days) was more frequent with S-LAAO (40.8% vs. 34.7%; odds ratio 1.29, 95% confidence interval: 1.13 - 1.47). Addition of S-LAAO did not increase mortality but was linked to greater inotrope use, warranting further investigation.
Tonegawa‐Kuji et al. (Tue,) conducted a cohort in Valve or coronary bypass surgery (n=25,059). Surgical left atrial appendage occlusion (S-LAAO) vs. No S-LAAO was evaluated on Prolonged inotropic support (≥ 2 days) (OR 1.29, 95% CI 1.13 - 1.47). Surgical left atrial appendage occlusion during cardiac surgery was associated with more frequent prolonged inotropic support (40.8% vs. 34.7%; OR 1.29, 95% CI 1.13-1.47) compared to no S-LAAO.