Key result
Intravenous magnesium sulfate completely abolished torsade de pointes in all 12 patients, but was ineffective in 5 patients with polymorphous ventricular tachycardia and normal QT intervals.
Why the study?
Does intravenous magnesium sulfate abolish torsade de pointes in patients with marked QT prolongation?
Population
17 patients total: 12 consecutive patients who developed torsade de pointes over a 4 year period, and 5…
Design
Case_series
Follow-up
up to 48 hours
Authors
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May support magnesium for TdP with QT prolongation; leaves open randomized confirmation in broader VT.
Observational (n=17)
Does intravenous magnesium sulfate abolish torsade de pointes in patients with marked QT prolongation?
Intravenous magnesium sulfate is a highly effective, rapid, and safe first-line therapy for abolishing torsade de pointes, but is ineffective for polymorphous ventricular tachycardia with a normal QT interval.
Tzivoni et al. (1988) conducted an observational in Torsade de pointes (n=17). Magnesium sulfate was evaluated on Complete abolition of torsade de pointes. Intravenous magnesium sulfate completely abolished torsade de pointes in all 12 patients, but was ineffective in 5 patients with polymorphous ventricular tachycardia and normal QT intervals.
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