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Case report highlights 68Ga FAPI PET/CT's superior contrast in identifying a pituitary abscess from tuberculosis.
Pituitary abscess is a rare, life-threatening condition of the sella, accounting for less than 1% of all pituitary lesions. We present the first case documenting 68Ga FAPI uptake in a pituitary abscess, in conjunction with 18F FDG PET/CT. While both tracers localized the lesion, 68Ga FAPI PET/CT demonstrated intense avidity against a negligible physiological background in the brain, thereby enhancing the contrast and detectability of this often-minuscule lesion. This superior tumor-to-background contrast highlights the potential of 68Ga FAPI PET/CT for the high-contrast visualization of infectious/inflammatory sellar lesions.
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Mandal et al. (2026) studied this question.
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