Key result
Sleep-disordered breathing drives cardiovascular risk through chronic sympathetic overactivity and systemic inflammation.
Why the study?
This review delineates the critical neural and cellular pathways connecting sleep, autonomic dysregulation, and cardiovascular risk.
This review delineates the critical neural and cellular pathways connecting sleep, autonomic dysregulation, and cardiovascular risk, emphasizing sleep disorders as independent drivers of cardiovascular disease.
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May inform CV risk stratification in sleep-disordered breathing; extends mechanistic insights but leaves open need for intervention trials.
Karim et al. (2026) conducted a review in Cardiovascular Disease and Sleep Disorders. Sleep-disordered breathing and sleep disturbances was evaluated. Sleep-disordered breathing and related disturbances provoke chronic sympathetic overactivity and systemic inflammation, providing a direct mechanistic link to elevated cardiovascular risk.
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