Mitral Valve Surgery After Failed MitraClip: A Single-Center Experience
Key result
Surgical mitral valve repair after failed MitraClip resulted in similar intermediate-term mortality compared to mitral valve replacement (30% vs 27%; P=.90).
Why the study?
Percutaneous mitral repair with MitraClip is safe and effective, but some patients require subsequent mitral surgery for recurrence of significant MR, prompting evaluation of candidacy for surgical MV repair after failed MitraClip.
Is surgical mitral valve repair feasible and safe compared to replacement in patients with severe symptomatic mitral regurgitation after failed MitraClip?
Comparison
MV repair vs MV replacement
Design
Single-center observational study
Authors
Discussion
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Member takes
Implication
Similar mortality after repair or replacement post-failed MitraClip supports individualized decisions; leaves open optimal strategy in larger prospective studies.
Study Design
Type
Observational (n=25)
Multicenter
No
Structured PICO
Is surgical mitral valve repair feasible and safe compared to replacement in patients with severe symptomatic mitral regurgitation after failed MitraClip?
P
Population
25 patients (mean age 69 years, 52% women) with severe symptomatic mitral regurgitation who underwent mitral surgery after a median interval of 5.1 months following failed MitraClip.
E
Exposure
Mitral valve surgery (10 underwent mitral valve repair, 15 underwent mitral valve replacement).
C
Comparator
Mitral valve repair versus mitral valve replacement.
O
Outcome
Feasibility of surgical mitral valve repair, perioperative complications, and intermediate-term mortality.hard clinical
Main Result
Absolute Event Rate: 30% vs 27%
p-value: p=.90
Surgical mitral valve repair is feasible and yields similar intermediate-term mortality to valve replacement in selected patients after failed MitraClip.
Cite This Study
Rader et al. (2021) conducted an observational in Severe symptomatic mitral regurgitation after failed MitraClip (n=25). Surgical mitral valve repair vs. Surgical mitral valve replacement was evaluated on Intermediate-term mortality (p=.90). Surgical mitral valve repair after failed MitraClip resulted in similar intermediate-term mortality compared to mitral valve replacement (30% vs 27%; P=.90).