Key result
Transcatheter aortic valve implantation offers better mortality outcomes compared with surgical aortic valve replacement for severe symptomatic aortic stenosis, but carries a higher risk of stroke.
Why the study?
Severe aortic stenosis requires early intervention, and selecting between transcatheter aortic valve replacement and surgical aortic valve replacement requires evaluating clinical features and adverse effects.
Does transcatheter aortic valve replacement reduce adverse effects compared to surgical aortic valve replacement in elderly patients with severe aortic stenosis?
Does transcatheter aortic valve replacement reduce adverse effects compared to surgical aortic valve replacement in elderly patients with severe aortic stenosis?
This review summarizes the management of severe aortic stenosis, comparing TAVR and SAVR with a focus on adverse effects and current guidelines.
May inform shared decision-making for severe AS; leaves open need for updated randomized data on stroke risk.
Severe aortic stenosis (AS) affects 3.4% of the elderly over 60 years of age. It presents with exertional dyspnea, syncope, angina, and progression to irreversible congestive heart failure. Early intervention produces a better outcome in preventing the clinical deterioration of AS. The choice of intervention is transcatheter aortic valve implantation or surgical aortic valve replacement (SAVR). The decision should be made after evaluating an individual case based on its clinical features and the user's experience with transcatheter aortic valve replacement (TAVR). We reviewed available data to illustrate the types of ASs, the background of interventions, current guidelines for TAVR, and its comparison with SAVR in terms of adverse effects.
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Sattar et al. (2019) conducted a review in Severe aortic stenosis. Transcatheter Aortic Valve Replacement (TAVR/TAVI) vs. Surgical Aortic Valve Replacement (SAVR) was evaluated. Transcatheter aortic valve implantation offers better mortality outcomes compared with surgical aortic valve replacement for severe symptomatic aortic stenosis, but carries a higher risk of stroke.
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