Key result
Intravenous amlodipine reduced left ventricular afterload and improved cardiac pumping performance in patients with stable coronary artery disease.
Why the study?
Does intravenous amlodipine improve haemodynamic parameters in patients with stable coronary artery disease?
Population
32 patients with stable coronary artery disease
Comparison
Amlodipine 20 mg i.v. vs Baseline measurements (before drug treatment)
Design
Cohort
Follow-up
10 to 15 minutes after administration
Authors
Loading...
Should not yet change practice in stable CAD; leaves open need for randomized confirmation of haemodynamic effects.
Does intravenous amlodipine improve haemodynamic parameters in patients with stable coronary artery disease?
Intravenous amlodipine reduces left ventricular afterload and improves cardiac pumping performance in patients with stable coronary artery disease.
Silke et al. (1990) studied Coronary artery disease (n=32). Amlodipine vs. Baseline (pre-treatment) was evaluated on Haemodynamic and radionuclide parameters (including systemic arterial blood pressure, vascular resistance index, and cardiac index). Intravenous amlodipine reduced left ventricular afterload and improved cardiac pumping performance in patients with stable coronary artery disease.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: