Key result
Preinfarction angina duration of <7 days versus ≥7 days was not significantly associated with well-developed coronary collaterals in patients with acute myocardial infarction (50.8% vs 75.0%, p=0.124).
Why the study?
Does the duration of preinfarction angina correlate with the development of coronary collateral circulation in patients with acute myocardial infarction?
Cross-Sectional (n=73)
No
Does the duration of preinfarction angina correlate with the development of coronary collateral circulation in patients with acute myocardial infarction?
Absolute Event Rate: 50.8% vs 75%
p-value: p=0.124
The duration of preinfarction angina does not appear to be significantly related to the presence of well-developed coronary collateral circulation in patients with acute myocardial infarction.
Similar collateral rates with <7 vs ≥7 days preinfarction angina; challenges assumptions on required symptom duration for protection.
Background: Coronary collateral circulation conduits an alternative blood flow to the ischemic myocardium in the setting of coronary artery occlusion which can prevent the infarction area to extend more widely. Well-developed coronary collaterals are closely related with the presence of preinfarction angina. However, the duration of preinfarction angina which can induce well-developed coronary collateralization is in controversy. The aim of this study was to evaluate the relation between duration of preinfarction angina and coronary collaterals circulation in patients with acute myocardial infarction. Methods: This cross-sectional study was conducted from May to November 2013 in Dr. Hasan Sadikin General Hospital, Bandung, Indonesia. Seventy three acute myocardial infarction (AMI) patients were included in the study. The patients were divided into Group 1 (<7 days) and Group 2 (≥7 days) based on their preinfarction angina history. The coronary collaterals were assesed and graded as good (Rentrop score 2−3) and poor (Rentrop score 0−1).Statistical analysis was performed using the chi-square test. Result: The presence of a well-developed coronary collateral was not significantly different in <7days than ≥7 days duration of preinfarction angina [50.8% v 75.0%, p=0.124]. Conclusions: There is no relation between the duration of preinfarction angina and coronary collaterals circulation in patients with acute myocardial infarction.
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Shidiq et al. (2016) conducted a cross-sectional in acute myocardial infarction (n=73). Preinfarction angina duration <7 days vs. Preinfarction angina duration ≥7 days was evaluated on Presence of a well-developed coronary collateral (Rentrop score 2-3) (p=0.124). Preinfarction angina duration of <7 days versus ≥7 days was not significantly associated with well-developed coronary collaterals in patients with acute myocardial infarction (50.8% vs 75.0%, p=0.124).
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