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June 27, 2026BioNanoScienceOpen Access

Application of Hyaluronic Acid in Enhancing the Efficacy and Safety of Paclitaxel Nanoformulations for Cancer Treatment: A Recent Review

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Authors

ABAlmigdad M. A. BallalJNJoshua C. NwabuifeWSWilliam S. Serumula

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Overview

Recent review highlights how hyaluronic acid improves paclitaxel's effectiveness in cancer therapy, suggesting new treatment strategies.

Key Points

  • This review aims to summarize how hyaluronic acid enhances the therapeutic effects of paclitaxel in cancer treatment.
  • Review of strategies using hyaluronic acid for enhancing paclitaxel efficacy
  • Discussion of ligand-receptor targeting with CD44
  • Examination of various drug delivery systems including self-assembly and functionalized nanoparticles.
  • Hyaluronic acid significantly improves the solubility and safety profile of paclitaxel
  • Enhanced tumor selectivity observed through CD44 targeting
  • Various nanoformulation approaches show promise for future therapeutic applications.

Cite This Study

Ballal et al. (2026) studied this question.

synapsesocial.com/papers/6a3f6972aea7db3c195404a3https://doi.org/10.1007/s12668-026-02653-y
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