Key result
Ingestion of a 45-g fat meal significantly increased RLP-C and RLP-TG levels in all hypertriglyceridemic patients, with type III patients having significantly higher levels in both fasted and fed states (P<0.01).
Why the study?
Does ingestion of a fat meal differentially affect postprandial RLP and TG levels in patients with different forms of hypertriglyceridemia?
Population
45 patients with hypertriglyceridemia having similarly elevated serum TG levels, divided into three groups…
Comparison
Ingestion of a 45-g fat meal vs Fasting state (baseline)
Design
Cohort
Follow-up
6 hours
Authors
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Postprandial RLP-C/TG elevations appear greater in type III hypertriglyceridemia; hypothesis-generating for phenotype-specific dietary strategies but should not yet change practice.
Observational (n=45)
Does ingestion of a fat meal differentially affect postprandial RLP and TG levels in patients with different forms of hypertriglyceridemia?
p-value: p=<0.01
Marcoux et al. (2000) conducted an observational in Hypertriglyceridemia (n=45). 45-g fat meal vs. Fasted state was evaluated on Postprandial changes in remnant-like particle (RLP) levels and total serum triglyceride (TG) (p=<0.01). Ingestion of a 45-g fat meal significantly increased RLP-C and RLP-TG levels in all hypertriglyceridemic patients, with type III patients having significantly higher levels in both fasted and fed states (P<0.01).
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