Key result
Intravenous propranolol increases exercise tolerance by ~60% in patients with angina pectoris.
Why the study?
Does intravenous propranolol improve exercise tolerance in patients with angina pectoris?
Observational (n=20)
Open-label
No
Does intravenous propranolol improve exercise tolerance in patients with angina pectoris?
This early preliminary report demonstrates that beta-adrenergic blockade with propranolol significantly improves exercise tolerance in patients with stable angina pectoris.
Answers are grounded in this paper and cite their sources.
May support IV propranolol for angina-limited exercise; leaves open need for randomized confirmation before clinical adoption.
There is evidence that this drug is helpful in angina pectoris
No takes yet. Share an insight, caveat, or question.
Hamer et al. (1964) conducted an observational in Angina Pectoris (n=20). Propranolol vs. Baseline (self-controlled test before drug) was evaluated on Total work performed on bicycle ergometer until limited by angina or fatigue (60% increase, p=<0.01). Intravenous propranolol significantly increased exercise tolerance (total work performed) by 60% (p<0.01) in patients limited by angina pectoris.
Synapse has enriched 10 related papers. Consider them for comparative context: