What question did this study set out to answer?

The research aims to develop a sensitive scale for measuring disease progression in advanced Alzheimer's disease.

Measurement of Severity in Advanced Alzheimer's Disease

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Randomized trial evaluates BANS-S scale for assessing severity in advanced Alzheimer's disease, suggesting clinical relevance.

The research aims to develop a sensitive scale for measuring disease progression in advanced Alzheimer's disease.
Combined cognitive and functional ratings alongside pathological symptoms to create BANS-S scale.
Tested BANS-S on 74 patients in three Special Care Dementia Units.
Correlated BANS-S scores with established cognitive tests and post-mortem findings.
BANS-S demonstrated good reliability and reproducibility for measuring severity.
Scores correlated with Mini-Mental State Examination, Katz ADL, and other assessments.
In 25 patients, BANS-S scores correlated with neurofibrillary tangles density in hippocampal areas.

Volicer et al. (1994) studied this question.

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