Key result
The presence of a non-flow limiting dissection following successful drug-coated balloon treatment of de novo coronary lesions was not associated with increased late lumen loss at 6 months (0.05 mm vs 0.05 mm, p=0.886).
Why the study?
Dissection after balloon angioplasty achieves luminal gain but carries vascular risk; the relationship between non-flow limiting dissections and subsequent lumen loss or long-term clinical outcomes after drug-coated balloon treatment of de novo coronary lesions was unclear.
Does the presence of a non-flow limiting dissection after successful drug-coated balloon treatment of de novo coronary lesions affect late lumen loss or target vessel failure?
Cohort (n=227)
Yes
Does the presence of a non-flow limiting dissection after successful drug-coated balloon treatment of de novo coronary lesions affect late lumen loss or target vessel failure?
Mean Difference: 0
Absolute Event Rate: 0.05% vs 0.05%
p-value: p=0.886
Non-flow limiting dissections remaining after successful drug-coated balloon treatment of de novo coronary lesions appear to heal well and do not adversely impact long-term angiographic or clinical outcomes.
No takes yet. Share an insight, caveat, or question.
Non-flow-limiting dissections after DCB were not associated with LLL or TVF; leaves open whether stenting can be safely avoided.
Lin et al. (2020) conducted a cohort in De novo coronary lesions (n=227). Non-flow limiting coronary dissection after drug-coated balloon treatment vs. No dissection was evaluated on Late lumen loss (LLL) at 6-month angiography (p=0.886). The presence of a non-flow limiting dissection following successful drug-coated balloon treatment of de novo coronary lesions was not associated with increased late lumen loss at 6 months (0.05 mm vs 0.05 mm, p=0.886).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: