Why the study?
Attempting to separate fibrous adhesions binding multiple leads during transvenous lead extraction with a cutting sheath can increase procedural complexity and risk.
Does the TWIX technique allow safe and effective simultaneous extraction of two pacemaker leads through a single sheath in patients undergoing transvenous lead extraction?
Does the TWIX technique allow safe and effective simultaneous extraction of two pacemaker leads through a single sheath in patients undergoing transvenous lead extraction?
Answers are grounded in this paper and cite their sources.
The novel TWIX technique allows for the safe and effective simultaneous extraction of two pacemaker leads through a single sheath, potentially reducing procedural complexity and tissue injury.
Background Transvenous lead extraction (TLE) is technically demanding procedure that carries risk of serious complications. In many cases multiple leads require removal. Fibrous adhesions frequently bind the leads together, and attempting to separate them with a cutting sheath may increase procedural complexity and risk—particularly with longer dwell times. Purpose To describe a series of TLE procedures, using the "TWIX technique", in which two pacemaker leads are extracted together, through a single sheath. Methods Four patients underwent TLE due to local or systemic infection: two with dual-chamber pacemakers, one with an ICD and one with a CRTD. In all cases, the pair extracted together consisted of a right atrial (RA) and a right ventricular (RV) pacemaker lead with passive fixation (one case had an active-fixation RA lead). Lead dwell time ranged from 9–21 years (median 14.8 years). An external sheath was advanced over both leads, each secured with a locking stylet. A mechanical rotating sheath (Tight Rail, 14 F) was used in two cases, and a laser sheath (16 F) in the other two. ICD defibrillation leads (two patients) and coronary sinus lead (one patient) were extracted separately Results All targeted leads were successfully extracted without clinically significant cardiac or vascular injury and without lead disruption. In three cases, the RA and RV leads were removed in block. Prominent inter-lead adhesions were observed (Figure). In one case, the RA lead disengaged first, and further sheath advancement was required to extract the RV lead. No significant adhesions between leads were noted in this case. Conclusion To our knowledge, this is the first report of a novel "TWIX technique" for simultaneous extraction of two pacemaker leads through a single sheath. In this small series of long-dwell leads, the approach was safe and effective, reduced the need for additional sheath advancement. This may significantly facilitate the procedure, shorten procedure time, and prevent vascular and cardiac tissue injury.
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Abuasbeh et al. (2026) studied this question.
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