Key result
Asymptomatic patients with type 2 diabetes had larger calcified coronary plaque volumes than healthy controls (11 vs. 3 μl; P=0.03), and baseline arterial stiffness correlated with plaque volumes.
Why the study?
Is baseline arterial stiffness associated with coronary plaque volumes at 5-year follow-up in asymptomatic patients with type 2 diabetes compared to healthy controls?
Population
106 asymptomatic participants, mean age 63 ± 10 years at follow-up.
Design
Cohort
Follow-up
5 years
Authors
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May support PWV for plaque risk stratification in diabetes; hypothesis-generating and requires prospective validation.
Observational (n=106)
Is baseline arterial stiffness associated with coronary plaque volumes at 5-year follow-up in asymptomatic patients with type 2 diabetes compared to healthy controls?
Absolute Event Rate: 11% vs 3%
p-value: p=0.03
In asymptomatic patients with type 2 diabetes, baseline arterial stiffness is independently associated with higher volumes of high-risk low-density noncalcified coronary plaques at 5-year follow-up.
Funck et al. (2017) conducted an observational in Type 2 diabetes without clinical signs of coronary artery disease (n=106). Type 2 diabetes vs. Healthy controls was evaluated on Calcified plaque volumes (μl) (p=0.03). Asymptomatic patients with type 2 diabetes had larger calcified coronary plaque volumes than healthy controls (11 vs. 3 μl; P=0.03), and baseline arterial stiffness correlated with plaque volumes.
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