Key result
Dietary sodium restriction increased carotid artery compliance by 46% and reduced resting systolic blood pressure by 12 mm Hg (P<0.01) in older adults with stage 1 systolic hypertension.
Why the study?
Does dietary sodium restriction improve large elastic artery compliance and reduce systolic blood pressure in older adults with stage 1 systolic hypertension?
Population
12 untreated, older (mean age 64+/-2 years) men and women (6 each) with stage 1 systolic hypertension.
Comparison
4 weeks of low dietary sodium intake vs 4 weeks of normal dietary sodium intake
Design
RCT, randomized, crossover design
Follow-up
4 weeks
Authors
Loading...
Sodium restriction rapidly improves arterial compliance in older systolic hypertension; extends RCT evidence to direct vascular function benefits.
RCT (n=12)
randomized, crossover design
Does dietary sodium restriction improve large elastic artery compliance and reduce systolic blood pressure in older adults with stage 1 systolic hypertension?
p-value: p=<0.01
Dietary sodium restriction rapidly improves large elastic artery compliance and reduces systolic blood pressure in older adults with stage 1 systolic hypertension.
Gates et al. (2004) conducted an RCT in stage 1 systolic hypertension (n=12). Dietary sodium restriction vs. Normal sodium intake was evaluated on Large elastic artery compliance (carotid artery compliance) and systolic blood pressure (p=<0.01). Dietary sodium restriction increased carotid artery compliance by 46% and reduced resting systolic blood pressure by 12 mm Hg (P<0.01) in older adults with stage 1 systolic hypertension.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: