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June 28, 2026AnimalsOpen Access

Integrated Multi-Omics Analysis Reveals the Physiological and Metabolic Response Mechanisms of Luciobarbus capito Under Cold Stress: Insights from Biochemical Parameters, Gut Microbiota, and Metabolomics

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Authors

KGKun GuoRZR. ZhangHWHaijun Wei

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Overview

Randomized trial evaluates biochemical, microbial, and metabolic responses in Luciobarbus capito under cold stress, indicating physiological challenges.

Key Points

  • This study aims to explore how cold stress affects biochemical, microbial, and metabolic responses in Luciobarbus capito.
  • Luciobarbus capito exposed to 12 °C for 96 h with control group at 22 °C
  • Analyzed hepatic antioxidant indices, serum biochemical parameters, and gut microbiota using 16S rRNA sequencing
  • Evaluated liver metabolomic profiles for differential metabolites.
  • Cold exposure decreased total superoxide dismutase and catalase activities, while malondialdehyde content increased
  • Serum ALT and AST activities increased, and acid phosphatase activity decreased
  • Identified 172 differential metabolites linked to various metabolic pathways, indicating significant physiological disruption.

Cite This Study

Guo et al. (2026) studied this question.

synapsesocial.com/papers/6a40b9c461bb0a67205c5da2https://doi.org/10.3390/ani16131971
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