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This research aimed to document the frequency and severity of depressive and anxiety symptoms in patients undergoing HSCT.

June 28, 2026CureusOpen Access

Depressive and Anxiety Symptoms at Initial Psychiatric Assessment in Patients Entering Hematopoietic Stem Cell Transplantation Protocols: A Cross-Sectional Study Using PHQ-9 and GAD-7

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Cross-sectional study identifies low depressive and anxiety symptoms in Mexican HSCT patients, suggesting early screening benefits.

This research aimed to document the frequency and severity of depressive and anxiety symptoms in patients undergoing HSCT.
Retrospective, cross-sectional observational study with 104 adult patients in an HSCT protocol.
Utilized PHQ-9 and GAD-7 scores for assessment of depression and anxiety.
Data analyzed included demographic data and hematological diagnosis.
Clinically significant depression was identified in 7.8% of patients with a median PHQ-9 of 0.
Clinically significant anxiety was present in 1.9% of patients with a median GAD-7 of 0.
Patients aged 18-35 years had a fourfold higher prevalence of mild anxiety compared to those aged 36-55 years (PR=4.2; p=0.026).

Salazar-Rodríguez et al. (2026) studied this question.

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