Case report shows endoscopic ultrasound biopsy identifies pyloric gland adenoma in a patient post-cholecystectomy, suggesting improved diagnostic methods.
Pyloric gland adenoma of the gallbladder is a rare benign lesion with malignant potential, often diagnosed postoperatively due to limited imaging specificity. We present a 67-year-old man with previous partial cholecystectomy found to have a suspicious gallbladder remnant lesion on imaging concerning for malignancy. Endoscopic ultrasound identified a 28.4 × 14 mm intraluminal mass, and fine-needle biopsy via a transduodenal approach confirmed pyloric gland adenoma with low-grade dysplasia. This case highlights the diagnostic utility of endoscopic ultrasound-guided biopsy in gallbladder lesions and emphasizes procedural considerations, including bile leak risk, while aiding surgical planning for lesions with neoplastic potential.
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Mohiuddin et al. (2026) studied this question.