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June 28, 2026The British Journal of PsychiatryOpen Access

Acceptability and accuracy of point-of-care monitoring of lithium levels

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Authors

MAMatthew AtkinsCLClarisse LagmanEOEbenezer Oloyede

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Overview

Randomized trial evaluates acceptability and accuracy of POCT for lithium in bipolar disorder, suggesting improved monitoring options.

Key Points

  • The study aims to assess patient and clinician attitudes towards point-of-care testing for lithium and to analytically validate a novel POCT device against a reference method.
  • Conducted surveys to gather patient and clinician attitudes on lithium monitoring and treatment.
  • Performed analytical validation of the Medimate Multireader device comparing it with a reference laboratory method.
  • Assessed accuracy, bias, agreement, and reproducibility in the device's performance.
  • Most respondents preferred point-of-care testing to traditional venous sampling.
  • The Medimate Multireader showed high analytical agreement with a correlation coefficient of 0.96 and mean bias within ±0.2 mmol/L.
  • Participants believed home-based POCT would increase their willingness to take lithium.

Cite This Study

Atkins et al. (2026) studied this question.

synapsesocial.com/papers/6a40bb4561bb0a67205c6d18https://doi.org/10.1192/bjp.2026.10695
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