What question did this study set out to answer?

This study investigates how the predictors of smoking cessation outcomes have changed over time, particularly due to cohort effects and evolving nicotine use patterns.

June 29, 2026Nicotine & Tobacco Research

Recent changes in effects of predictors of tobacco cessation in formal treatment

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Authors

SVScott VeldhuizenCentre for Addiction and Mental Health KIKameron IturraldeCentre for Addiction and Mental Health LZLaurie ZawertailoCentre for Addiction and Mental Health

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Implication

Randomized trial shows evolving predictors of smoking cessation outcomes in a large nicotine replacement program, indicating dynamic trends in treatment effectiveness.

Key Points

This study investigates how the predictors of smoking cessation outcomes have changed over time, particularly due to cohort effects and evolving nicotine use patterns.
Analyzed 8 years of data (2016-2024) from 107,204 enrollees in a nicotine replacement therapy program in Ontario, Canada.
Utilized generalized additive models for multiplicity-corrected tests of interactions.
Employed a backwards stepwise process to develop the final analysis model.
Cessation probability increased significantly over time for youth (9.7% increase at age 26, 95% CI = 5.0%, 14.4%).
Daily e-cigarette users experienced a 10.8% increase in cessation probability (95% CI = 1.7%, 19.8%).
There was a notable compression of cessation outcome differences across income levels.

Cite This Study

Veldhuizen et al. (2026) studied this question.

synapsesocial.com/papers/6a420b7af91bb43ea9192948 https://doi.org/10.1093/ntr/ntag147

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Implication

Randomized trial shows evolving predictors of smoking cessation outcomes in a large nicotine replacement program, indicating dynamic trends in treatment effectiveness.

Recent changes in effects of predictors of tobacco cessation in formal treatment

Discussion

Member takes

Implication

Key Points

Cite This Study

Recent changes in effects of predictors of tobacco cessation in formal treatment

Discussion

Member takes

Implication

Key Points

Cite This Study

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