What question did this study set out to answer?

To identify predictors of continuous smoking abstinence at medium-term (24 weeks) and long-term (52 weeks) follow-up and assess whether these predictive factors persist over time.

November 3, 2025Tobacco Prevention & CessationOpen Access

Do predictors of abstinence change in the medium- and long-term follow-up of smokers who have quit smoking? A prospective cohort study

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Authors

JGJosé Ignacio de Granda‐OriveUniversidad Complutense de Madrid CRCarlos A. Jiménez RuizHospital Clínico San Carlos MCMaría Isabel Cristobal-Fernández

Discussion

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Implication

Prospective cohort study reveals key predictors of continuous abstinence in adult smokers, indicating treatment adherence consistently drives long-term cessation.

Key Points

To identify predictors of continuous smoking abstinence at medium-term (24 weeks) and long-term (52 weeks) follow-up and assess whether these predictive factors persist over time.
Conducted an observational prospective multicenter cohort study in daily clinical practice in Spain, consecutively enrolling smokers and following them for 12 months (N=337).
Collected baseline sociodemographic, clinical, smoking history, and psychological and physical dependence variables, analyzing outcomes by intention to treat using multivariate logistic regression models.
Predictors of cessation at 24 weeks were baseline weight (AOR=1.02; 95% CI: 1.00–1.03), having no previous quit attempts (AOR=2.72; 95% CI: 1.44–5.15), lower sedation levels on psychological dependence tests (AOR=1.78; 95% CI: 1.06–2.97), and treatment adherence (AOR=8.03; 95% CI: 3.85–16.73).
Predictors at 52 weeks included male sex (AOR=2.38; 95% CI: 1.35–4.18), low self-efficacy (AOR=2.60; 95% CI: 1.36–5.00), no prior quit attempts (AOR=5.06; 95% CI: 2.20–11.66), lower sedation levels (AOR=1.96; 95% CI: 1.13–3.40), and treatment adherence (AOR=12.03; 95% CI: 4.14–34.94).
Three factors maintained predictive power across both the 24-week and 52-week endpoints: zero previous quit attempts, lower psychological sedation levels, and high adherence to prescribed treatment.

Cite This Study

Granda‐Orive et al. (2025) studied this question.

synapsesocial.com/papers/6aaba912430309c6f8c079ba https://doi.org/10.18332/tpc/208884

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Implication

Prospective cohort study reveals key predictors of continuous abstinence in adult smokers, indicating treatment adherence consistently drives long-term cessation.

Do predictors of abstinence change in the medium- and long-term follow-up of smokers who have quit smoking? A prospective cohort study

Discussion

Member takes

Implication

Key Points

Cite This Study

Do predictors of abstinence change in the medium- and long-term follow-up of smokers who have quit smoking? A prospective cohort study

Discussion

Member takes

Implication

Key Points

Cite This Study

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