Key result
Passive leg raising significantly increased mean cardiac index by 0.09 L/min.m2 (p<0.001), though only 16% of patients had an increase greater than 10%.
Why the study?
Does passive leg raising significantly increase cardiac output and alter hemodynamic parameters in patients?
Observational (n=45)
Does passive leg raising significantly increase cardiac output and alter hemodynamic parameters in patients?
Mean Difference: 0.09
p-value: p=<0.001
Passive leg raising produces only a minimal increase in cardiac index in the majority of patients.
Minimal response in most patients cautions against routine use; leaves open targeted validation in future studies.
Cardiac output by thoracic bioimpedance, heart rate, BP, oxygen saturation, and transcutaneous oxygen tension were measured at 1-min intervals in 45 patients before and after passive leg raising (PLR). Mean cardiac index increased only 0.09 +/- 0.02 (SEM) L/min.m2 (p less than .001), mean transcutaneous oxygen tension increased 1.6 +/- 0.6 torr (p less than .01), and mean oxygen saturation decreased 0.5 +/- 0.2% (p less than .01) after PLR. There were no significant changes in heart rate or systolic BP. Seven (16%) patients had increased cardiac index greater than 10% after PLR.
No takes yet. Share an insight, caveat, or question.
WONG et al. (1988) reported an observational. Passive leg raising (PLR) vs. Before PLR (baseline) was evaluated on Mean cardiac index (MD 0.09, p=<0.001). Passive leg raising significantly increased mean cardiac index by 0.09 L/min.m2 (p<0.001), though only 16% of patients had an increase greater than 10%.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: