Changes in cardiac output after acute blood loss and position change in man

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Why the study?

Does passive leg raising increase cardiac output in humans after acute blood loss?

Structured PICO

Does passive leg raising increase cardiac output in humans after acute blood loss?

Population

27 volunteers

Intervention

Acute blood withdrawal of 500 ml (3.7 to 8.5 ml/kg; mean 5.8) and position change (passive leg raising and standing)

Comparator

Baseline measurements before blood withdrawal and before position change

Outcome

Thoracic bioimpedance cardiac output (Qtbi) and cardiac index (CI)surrogate

Passive leg raising significantly increases stroke volume and cardiac output in hypovolemic humans following acute blood loss.

No takes yet. Share an insight, caveat, or question.

PLR may augment cardiac index after blood loss; hypothesis-generating, should not yet change practice.

WONG et al. (1989) studied this question.

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