Key result
Withdrawal of 16% of blood volume resulted in a smaller fractional reduction in forearm vascular resistance during contralateral isometric handgrip compared to the normovolaemic state.
Why the study?
Does moderate blood loss alter peripheral vascular reactivity during contralateral isometric handgrip in healthy males?
Does moderate blood loss alter peripheral vascular reactivity during contralateral isometric handgrip in healthy males?
Moderate hypovolemia alters the peripheral vascular reactivity to contralateral isometric handgrip, likely due to changes in sympathetic or beta-adrenergic activity.
No takes yet. Share an insight, caveat, or question.
Small study in healthy males leaves open whether moderate blood loss alters vascular reactivity; prospective data needed.
Bergenwald et al. (1977) studied Healthy (n=8). Withdrawal of blood volume vs. Normovolaemic state (before withdrawal) was evaluated on Circulatory response to contralateral isometric handgrip (heart rate, arterial pressures, forearm and calf blood flow, vascular resistance). Withdrawal of 16% of blood volume resulted in a smaller fractional reduction in forearm vascular resistance during contralateral isometric handgrip compared to the normovolaemic state.
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