Why the study?
Does a handgrip-induced rise in arterial blood pressure alter calf blood flow at rest and during reactive hyperemia in healthy subjects?
Does a handgrip-induced rise in arterial blood pressure alter calf blood flow at rest and during reactive hyperemia in healthy subjects?
An acute increase in arterial blood pressure via handgrip exercise significantly increases maximal calf blood flow and decreases peripheral resistance during reactive hyperemia.
Acute handgrip may augment calf hyperemia in healthy subjects; hypothesis-generating for pressure-flow dynamics, needs disease-state validation.
The influence of a handgrip-induced rise in arterial blood pressure on the blood flow in the calf at rest and on the maximal flow during reactive hyperemia after 5-minute arterial occlusion was studied in 7 healthy subjects. Isometric contractions of the forearm muscles (handgrip) with 20% of the maximal voluntary contraction during 3 minutes caused a significant increase in mean blood pressure of 19% (SEM 3%; p less than 0.05). No significant increase in the mean blood flow at rest was found. The maximal blood flow during reactive hyperemia was increased by 42% (SEM, 5%; p less than 0.05). The lowest peripheral resistance during reactive hyperemia was decreased by 15% (SEM 6%; p less than 0.05).
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Barendsen et al. (1981) studied this question.
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