Key result
LDL/HDL ratio was significantly associated with the risk of in-stent restenosis in patients with acute coronary syndrome after stent implantation (OR ≈ 2.00; p < 0.05).
Why the study?
The relationship between LDL/HDL ratio and in-stent restenosis in acute coronary syndrome was unknown.
Does the LDL/HDL ratio predict in-stent restenosis in patients with acute coronary syndrome after stent implantation?
Observational (n=256)
Does the LDL/HDL ratio predict in-stent restenosis in patients with acute coronary syndrome after stent implantation?
Odds Ratio: 2
p-value: p=< 0.05
The LDL/HDL ratio serves as a significant independent predictor of in-stent restenosis in patients with acute coronary syndrome following stent implantation.
LDL/HDL ratio independently associated with ISR in ACS; hypothesis-generating and requires prospective validation before clinical use.
Background: The relationship between LDL/HDL ratio and in-stent restenosis in acute coronary syndrome is unknown. Methods: This observational study recruited 256 patients with acute coronary syndrome who were being followed up by angiography after stenting. The patients were divided into in-stent restenosis (59%) and non-in-stent restenosis (41%) groups. Three stepwise multivariate logistic regression models and area under the curve were conducted to determine the role of LDL/HDL ratio in predicting in-stent restenosis. Results: LDL/HDL ratio was significantly associated with risk of in-stent restenosis (odds ratio ≈ 2.00; p < 0.05 for all) in three models. A good predictive performance of LDL/HDL ratio on in-stent restenosis was found with an area under the curve of 0.74. Conclusion: LDL/HDL ratio was independently associated with the risk of in-stent restenosis in acute coronary syndrome.
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Yang et al. (2022) conducted an observational in Acute Coronary Syndrome (n=256). LDL/HDL ratio was evaluated on In-stent restenosis (OR ≈ 2.00, p=< 0.05). LDL/HDL ratio was significantly associated with the risk of in-stent restenosis in patients with acute coronary syndrome after stent implantation (OR ≈ 2.00; p < 0.05).
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