What question did this study set out to answer?

This review aims to assess the effectiveness and clinical implications of AI-based radiomics for mediastinal lymph node staging in non-small cell lung cancer.

June 30, 2026DiagnosticsOpen Access

Artificial Intelligence-Based 18F-FDG PET/CT Radiomics for Mediastinal Lymph Node Staging in Non-Small Cell Lung Cancer: A Systematic Review

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Authors

ARAlessia-Stephania RoșianVictor Babeș University of Medicine and Pharmacy Timișoara APA. PusztaiVictor Babeș University of Medicine and Pharmacy Timișoara ACAmalia ConstantinescuVictor Babeș University of Medicine and Pharmacy Timișoara

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Implication

Systematic review evaluates AI-based imaging techniques for staging lymph nodes in non-small cell lung cancer, indicating their potential utility.

Key Points

This review aims to assess the effectiveness and clinical implications of AI-based radiomics for mediastinal lymph node staging in non-small cell lung cancer.
Conducted systematic literature search in PubMed, ScienceDirect, and Scopus per PRISMA guidelines.
Included studies utilized AI-based radiomic approaches with histopathology as reference standard.
Evaluated methodological quality using the QUADAS-2 tool.
Thirteen studies with retrospective designs included, cohort sizes from 87 to 3265 patients.
Composite models integrating radiomic and clinical factors outperformed radiomics-only models.
AI approaches addressing false-positive FDG uptake improved specificity compared to conventional PET/CT.

Cite This Study

Roșian et al. (2026) studied this question.

synapsesocial.com/papers/6a435c65759b888809a52cdb https://doi.org/10.3390/diagnostics16132014

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Implication

Systematic review evaluates AI-based imaging techniques for staging lymph nodes in non-small cell lung cancer, indicating their potential utility.

Artificial Intelligence-Based 18F-FDG PET/CT Radiomics for Mediastinal Lymph Node Staging in Non-Small Cell Lung Cancer: A Systematic Review

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Cite This Study

Artificial Intelligence-Based 18F-FDG PET/CT Radiomics for Mediastinal Lymph Node Staging in Non-Small Cell Lung Cancer: A Systematic Review

Discussion

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Implication

Key Points

Cite This Study

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